Chances Of Breast Cancer Coming Back After Mastectomy

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Chances Of Breast Cancer Coming Back After Mastectomy – Women with early-stage breast cancer who underwent mastectomy (right panel) reported poorer quality of life than women who did not have mastectomy (left panel).

The type of surgery that young women with breast cancer in the initial stage can affect their quality of life years later, according to a new study.

Chances Of Breast Cancer Coming Back After Mastectomy

Chances Of Breast Cancer Coming Back After Mastectomy

Women who had surgery to remove one or both breasts (unilateral or bilateral mastectomy) had lower scores on quality of life surveys, indicating a poorer quality of life than women who had surgery to remove the tumor and nearby healthy tissue (breast conserving surgery). ), the researchers found.

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Researchers sent a questionnaire called BREAST-Q to 560 breast cancer survivors (age 40 or younger at diagnosis) to complete as part of their follow-up. The women were asked about a variety of topics, including satisfaction with their breasts after surgery, emotional well-being (such as anxiety levels) and sexual well-being.

In each of these areas, the answer is different depending on whether the woman had a mastectomy, a unilateral mastectomy or a bilateral mastectomy. Women who had a mastectomy followed by radiation therapy reported the lowest scores, indicating a poorer quality of life, according to findings published in

Laura Dominici, MD, a surgeon at the Dana-Farber Brigham Center who led the study said: “The choice of surgery that women with breast cancer make can affect their long-term quality of life.

“As doctors, we have to talk to our patients about surgical options to understand how the treatment they choose can affect their quality of life,” said Dr. Dominici.

Breast Reconstruction After Mastectomy

Women diagnosed with early stage breast cancer can choose between surgical treatment. Studies have shown that different surgical methods have similar survival rates and risk of recurrence. Surgical complications, however, are more frequent in mastectomy than in breast conservation surgery.

Despite the similar results, a growing number of women in the United States with early-stage breast cancer choose mastectomy. This includes women with an early stage in one breast who choose to undergo a prophylactic contralateral mastectomy – surgery to remove the other (healthy) breast.

In fact, most of the study participants had early-stage breast cancer and many would be candidates for breast-conserving surgery, such as a mastectomy, explains Dr. Dominici. However, 72% chose mastectomy (20% chose unilateral mastectomy and 52% chose bilateral) and 28% chose breast conserving surgery.

Chances Of Breast Cancer Coming Back After Mastectomy

Study participants completed the BREAST-Q questionnaire an average of 5.8 years after diagnosis. Most were white, married, reported being financially comfortable and had a higher education.

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The questionnaire asks patients to rate a series of questions on a scale from 0 to 100, with higher scores representing more favorable outcomes.

In the area of ​​breast satisfaction, BREAST-Q asks women what they think about how their breasts fit, how they feel to the touch, and how they look in and out of clothes. The questionnaire also asks about women’s confidence in their social environment, emotional health and self-esteem.

The results of the new study should be incorporated into patient counseling, writes Monica Morrow, MD, a breast surgeon at Memorial Sloan Kettering Center, in an accompanying editorial.

The lower quality of life score after mastectomy compared with breast-conserving therapy should be included in discussions about the benefits of mastectomy versus breast-conserving therapy, Dr. Morrow added.

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She emphasized that women with breast cancer in the initial stage have a low risk of developing in the other breast (opposite). This information should be conveyed to patients with the lack of survival benefit and the risk of surgical complications with mastectomy, he wrote.

“Surgeons’ recommendations against contralateral prophylactic mastectomy are strong barriers to the use of the procedure,” he wrote.

As mastectomies have become more common, the use of radiation therapy after mastectomy has increased.

Chances Of Breast Cancer Coming Back After Mastectomy

In light of these trends, the study’s finding of decreased breast satisfaction among women who had a mastectomy — and especially among those who received radiation therapy after breast reconstruction — is “worrying,” the researchers wrote.

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“It is important for us to be able to tell patients that they may have a worse quality of life if they choose mastectomy and especially if they receive radiation after surgery,” said Dr.

The results of this study emphasize the importance of conducting research on survivors so that women who are considering breast surgery can be informed about quality of life issues, said Emily Tonorezos, MD, director of the NCI Survivorship Office.

“If women only consider the risk of recurrence, these surgical treatment options will be similar,” continued Dr. Tonorezos. “But an important difference arises when we consider long-term patient satisfaction and well-being.”

A limitation of the study was that participants only completed the questionnaire at one time, Dr. Tonorezos said. Another is that the researchers did not know the quality of life of the participants when they chose the surgery. The researchers do not know why the participants chose one treatment over another.

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The results cannot be broadly applied to women other than the type of patient in the study (for example, white, married, educated at university), the researchers noted.

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Chances Of Breast Cancer Coming Back After Mastectomy

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Czech women’s views on immediate breast reconstruction after mastectomy due to BRCA mutation or breast cancer

The Role Of Breast Mri In Detecting Asymptomatic Recurrence After Therapeutic Mastectomy

By Tomáš Ventruba Tomáš Ventruba Scilit Preprints.org Google Scholar View Publications 1, 2, Michal Ješeta Michal Ješeta Scilit Preprints.org Google Scholar View Publications 1, Luboš Minář Luboš Minář Scilit Preprints.org Google Scholar Jindiliich V. Publications Preprints.org View Publications 1, 3, Dagmar Brančíková Dagmar Brančíková Scilit Preprints.org Google Scholar View Publications 4, Jana Žáková Jana Žáková Scilit Preprints.org Google Scholar View Publications 1 and Pavel Venlarba ViewScilit Google Preprints Publication 1, Pavel Ventruba *

Department of Internal Medicine, Anemia and Cancer, Brno University Hospital and Masaryk University, 625 00 Brno, Czech Republic

Application: April 21, 2023 / Review: June 12, 2023 / Accepted: June 13, 2023 / Published: June 15, 2023

Chances Of Breast Cancer Coming Back After Mastectomy

(1) Objective: Breast cancer is the most common cancer in women and the incidence of the disease continues to increase. The issue of immediate breast reconstruction (IBR) in women with BRCA mutations and breast cancer is a hot topic. This study is based on the long-term experience of our workplace with the diagnosis and treatment of breast cancer in women. We use the possibility of oncoplastic surgery, including IBR. Our effort involved learning women’s perceptions of IBR mastectomy at the same time. (2) Method: We chose a quantitative research method of women’s perceptions through structured anonymous questionnaires. Of the 84 respondents who had undergone IBR, 36.9% were due to BRCA mutations and 63.1% were due to breast cancer. (3) Results: All respondents learned about the possibility of IBR before treatment or during treatment planning. Initial information was obtained from an oncologist. Women get more information about IBR from plastic surgeons. Before the surgery, all the interviewees already knew what IBR meant, as well as the payment of IBR by the health insurance. All respondents will again choose the IBR option. A total of 94.0% of women mentioned maintaining the integrity of the body as a reason to perform IBR, and 88.1% of women recognized the possibility of performing IBR with their tissues. (4) Conclusion: There are few specialized centers with specialized personnel in breast reconstruction surgery in the Czech Republic, especially those that perform IBR. Research shows that all patients are

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